‪Javier Ruiz-López‬ - ‪Google Scholar‬

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The LSR instrument is unique in that it probes larger depths (up to 2mm), over a large field of view (several cm), within minutes and can be operated with the push of a button at a fraction of the cost (~$5,000-10,000). Laser speckle rheology (LSR) offers a new, noncontact optical approach. LSR uses an inexpensive laser similar to a common laser pointer to shine laser light on tissue—plus a camera to image speckle Laser Speckle Rheology (LSR) offers a novel, non-contact optical approach for evaluating the frequency-dependent viscoelastic properties of hydrogels. In LSR, a coherent laser beam illuminates the specimen and a high-speed camera acquires the time-varying speckle images. We specifically focus on laser speckle rheology (LSR), a technology that quantifies the mechanical properties of tissues in a rapid, noncontact manner. Approach: In LSR, the shear viscoelastic modulus is measured from the time-variant speckle intensity fluctuations reflected off the tissue. Laser Speckle Rheology (LSR) offers a novel, non-contact optical approach for evaluating the frequency-dependent viscoelastic properties of hydrogels.

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We introduce a novel technology, termed laser speckle micro-rheology (LSM) that offers the unique capability to map the viscoelastic properties of the tissue microenvironment. This innovation will provide important insight into mechano-biology of disease progression. 2016-12-08 · Laser speckle rheology (LSR) is a new optical approach that can quantify the mechanical properties of materials in a non-contact manner by analyzing the temporal fluctuations of laser speckle intensities [7–16]. The technique consists of sending a laser beam into the sample and detecting a speckle pattern created by scattered waves. Brownian motion depends on the viscoelastic structure of the sample (it characterizes speed and distance the particle is free to explore). effectively measure tissue stiffness. Laser speckle rheology (LSR) offers a new, noncontact optical approach.

In LSR, a coherent laser beam illuminates the tissue and temporal speckle intensity fluctuations are analyzed to evaluate mechanical properties. The rate of temporal speckle fluctuations is, however, Laser speckle microrheology is used to determine a mechanical property of a biological tissue, namely, an elastic modulus.

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Laser Speckle Rheology (LSR) offers a novel, non-contact optical approach for evaluating the frequency-dependent viscoelastic properties of hydrogels. In LSR, a coherent laser beam illuminates the specimen and a high-speed camera acquires the time-varying speckle images. We introduce a novel technology, termed laser speckle micro-rheology (LSM) that offers the unique capability to map the viscoelastic properties of the tissue microenvironment. This innovation will provide important insight into mechano-biology of disease progression.

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Laser speckle rheology (LSR) offers a new, noncontact optical approach. Laser Speckle Rheology (LSR) offers a novel, non-contact optical approach for evaluating the frequency-dependent viscoelastic properties of hydrogels. In LSR, a coherent laser beam illuminates the Laser Speckle Rheology (LSR) offers a novel, non-contact optical approach for evaluating the frequency-dependent viscoelastic properties of hydrogels. In LSR, a coherent laser beam illuminates the specimen and a high-speed camera acquires the time-varying speckle images. 2015-03-01 · Laser speckle rheology (LSR) is an optical technique for assessing the viscoelastic properties of materials with several industrial, biological, and medical applications. In LSR, the viscoelastic modulus, G*(ω), of a material is quantified by analyzing the temporal fluctuations of speckle patterns.
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We specifically focus on laser speckle rheology (LSR), a technology that quantifies the mechanical properties of tissues in a rapid, noncontact manner.

MM Tripathi, Z Hajjarian, EM Van Cott, SK Nadkarni.
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